Effect of Garcinia binucao Crude Leaf Extract Supplementation on Lifespan of Drosophila melanogaster Chronically Exposed to Alcohol

Background. Consumption and abuse of alcohol remains a significant cause concern worldwide. Furthermore, there is evidence the association between chronic use reduced life expectancy.Objectives. To study effects Garcinia binucao extract (GBE) supplementation on lifespan Drosophilamelanogaster, in presence or absence exposure.Methods. D. melanogaster was mass cultured given GBE high (1 mg/mL) low (200 µg/mL) sublethal doses. flies were divided into groups - with without exposure, their respective lifespans monitored.Results. In mean highest control (38.15 days), followed by high-dose (34.42 low-dose (33.24 DMSO (22.29 days). chronically exposed to alcohol, longest observed treated (33.80 (33.63 group (30.30), (29.65 but differences not statistically significant. Comparing significantly decreased 9.51 days (p < 0.05). treatment groups, 0.82 set-up 0.05), increased 0.39 0.05) upon exposure.Conclusion. ameliorated reduction Drosophila alcohol. &nbsp